Sanctum of Loathing guide
A solo trial scored on time and deaths. Three rooms of monsters, then two bosses at once.
- Prep
Before you go
Sanctum of Loathing · Ascension Trial- Level
- 45
- Item level
- 1,000 · Challenge 2,500
Entry by difficultyEasy Normal Hard Challenge Level 45 45 45 45 Item level 1,000 1,500 2,000 2,500 Party Solo Solo Solo Solo Deaths allowed 5 3 2 2 Entries a week 3, shared 3, shared 3, shared 3, shared Open every other week: Nightmare Altar takes the weeks betweenOut of deaths or time, the run fails
Know this first- Open every other weekNightmare Altar takes the weeks between
- 3 entries a weekReset Wednesday 07:00 UTC, spent on entering
- Bring stagger skillsSwap bosses or use area hits
- Speed is scoreTime left and deaths set your Final Score
- Pull monsters into one packFinish them together so Wrath bites less
Watch a full runAscension Trial, Sanctum Of Loathing | Full Playthrough | Aion 2 · DefectiveGaming · 8 Oct 2026Chosen by us. Plays on YouTube when you press it.
- 1Pick a difficulty and go inEntering uses 1 of your 3 weekly entries.
- 2Clear room 1The door stays shut until every monster is dead.
- 3Take both orbsThey buff you for the run and open the way on.
- 4Beat the room timerOptional. Finish in time for another buff that lasts the run.
- 5Rooms 2 and 3Same again. Pull monsters into one pack for area skills.
- 6Climb to the portalThe last stretch needs no orbs.
Dodge the red floor markers and fill the stagger bar.
The fightBoth bosses stand together. Keep moving and out of the red. - Red markersStep out before it landsRed shapes show on the floor early
- Stagger barUse your stagger skillsThe gauge fills as you hit
The same fight, same arena. Share your hits between the two.
The fight- Swap targetsSwitch between the twoAlternating fills the bar faster
- Area skillsHit both at onceSplash fills the bar faster
- Finish
Collect your score
Rewards follow your final score- 7. Read your scoreClear points, difficulty bonus, time left and deaths.
- 8. Rewards follow the scoreA higher score pays more stones and chests.
Score 7,000+ pays 3,500 Enhance Stones and 14 Amplify Stone FragmentsStones, fragments and chests, no gear
- If it goes wrong
If you wipe
- Out of deaths5 on Easy, 3 on Normal
- Out of timeThe countdown ends and the run fails
- Leaving mid-runProgress resets, and the entry is already spent
- Wrath on hurt monstersBelow half health they hit 30% harder
- Skipping an orbThe next room stays shut
- Hard and ChallengeOnly 2 deaths allowed
Players' runs
Clear times, Kinah and loot per run from players who run Sanctum of Loathing with the tracker on. They load here when JavaScript is on.
Monsters
Questions
How many bosses are in the Sanctum of Loathing?
Two, fought at the same time: Featherstorm Duduri and Watchful Raptor Dodori. They wait behind three rooms of regular monsters. The Sanctum of Loathing is a solo Ascension Trial, which early previews called the Awakening Battle.
What item level do you need for the Sanctum of Loathing?
You need level 45 and an item level set by difficulty: 1,000 for Easy, 1,500 for Normal, 2,000 for Hard and 2,500 for Challenge. It is solo only.
How does difficulty work in the Sanctum of Loathing?
There are four difficulties on one layout, with no Exploration or Conquest split like an expedition. Higher ones raise the monsters from level 45 to 60, allow fewer deaths (5, 3, 2 and 2) and give a bigger score. Insane and Hell are in the game files but not offered on global.
When is the Sanctum of Loathing open?
It alternates weekly with Nightmare Altar. The Sanctum is open from 30 September, 14 October, 28 October, 11 November, 25 November and 9 December, each starting Wednesday 07:00 UTC. Your 3 entries refresh at that time.
What does the Sanctum of Loathing reward?
Rewards follow your Final Score: Enhance Stones, Amplify Stone Fragments, Growth Pet Chests and Ascension Binding Chests. There is no gear. A failed run scores only 10 points.
Sources. Written by Kinah Ledger in our own words, checked against Aion 2 Maps: Dungeons and raids, Aion 2 Maps: Seasons and chapters, Aion 2 Maps: Global differences, MetaBot: Sanctum of Loathing, Wikily: Sanctum of Loathing, Wikily: Season 1, Game8: Sanctum of Loathing, Game8: Ascension Trials, AllThings.how: Sanctum of Loathing, Fextralife: Ascension Trial, TheGamesWiki: Ascension Trial, DefectiveGaming (YouTube). Boss art, entry rules and loot from the game files via MetaBot.GG. Global version, checked 23 October 2026. Report a mistake

